Full Prescribing Information       |        Important Risk Information       |        Patient Medication Guide       |
When is constipation more than just constipation?
If you are having fewer than three bowel movements a week, that's a sign you may have constipation. But is it occasional or chronic? Many people experience occasional constipation, which can be uncomfortable, painful, and difficult to talk about. It's also part of being human.
Occasional constipation means your symptoms are sudden and last for a short time. But if your constipation is long-lasting or keeps coming back, it may be chronic.
If you notice you're having infrequent bowel movements, difficulty passing stools, or both, that may mean you're suffering from Chronic Idiopathic Constipation (CIC). If you're feeling belly pain or discomfort in association with constipation, you could be suffering from Irritable Bowel Syndrome with Constipation (IBS-C). It's important to share these symptoms with your doctor.
Speak with your doctor today.
It's understandable if you're hesitant to talk about your symptoms with your doctor.
Our Steps Toward Relief guide can help you start the conversation.

If your doctor determines that you have IBS-C or CIC, ask about LINZESS.

LINZESS is a once-daily capsule that may help adults proactively manage their symptoms. LINZESS may help relieve your symptoms of IBS-C or CIC by helping you feel less belly pain and have more frequent and complete bowel movements that are easier to pass.
Looking for relief?
We'll guide you through it. Check out a tool that could help you talk with your doctor about what's worked and what hasn't.
IMPORTANT RISK INFORMATION
Do not give LINZESS to children who are under 6 years of age. It may harm them.
You should not give LINZESS to children 6 to 17 years of age. It may harm them.
Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).
What is LINZESS?
LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children.
 
IMPORTANT RISK INFORMATION
Do not give LINZESS to children who are under 6 years of age. It may harm them.
You should not give LINZESS to children 6 to 17 years of age. It may harm them.
Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).
 
Before you take LINZESS, tell your doctor:
If you have any other medical conditions.
If you are pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
If you are breastfeeding or plan to breastfeed. It is not known if LINZESS passes into your breast milk.
About all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
Side Effects
LINZESS can cause serious side effects, including diarrhea, the most common side effect, which can sometimes be severe. Diarrhea often begins with the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

In addition, call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

How to Take LINZESS
Take LINZESS exactly as your doctor tells you to take it. Take LINZESS one time each day on an empty stomach, at least 30 minutes before your first meal of the day. Swallow LINZESS capsules whole. Do not break or chew the capsules. If you miss a dose, skip the missed dose. Just take the next dose at your regular time. Do not take 2 doses at the same time.

Storing LINZESS
Store LINZESS at room temperature (68°F to 77°F). It is important to keep LINZESS in the bottle it comes in. Keep the LINZESS bottle tightly closed, in a dry place, and keep the desiccant (the drying agent) in the bottle. Keep LINZESS out of the reach of children.

Please also see Medication Guide within full Prescribing Information.

Ask your doctor about LINZESS. For more information, call 1‑800‑LINZESS.

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